What is rheumatoid arthritis?

Rheumatoid arthritis (RA) is a chronic autoimmune condition that causes discomfort, swelling and stiffness in the lining of your joints. It most often affects joints in your fingers, hands, wrists, knees, ankles, feet and toes. Unlike other types of arthritis, RA typically affects joints on both sides of the body.

An autoimmune condition happens when the immune system, which normally protects the body, becomes confused and starts attacking healthy tissues. In rheumatoid arthritis, this happens when the immune system causes inflammation in the joints.

You can manage RA effectively if it is diagnosed early. However, if left untreated, the condition causes serious side effects, such as joint deformities and disability.

rheumatoid arthritis patients enjoying their day outside together

Rheumatoid arthritis symptoms

Signs and symptoms of rheumatoid arthritis may include:

  • Pain, aching or stiffness in more than one joint
  • Tender, warm, swollen joints
  • Stiffness, especially in the mornings or after periods of inactivity
  • Fatigue
  • Fever
  • Loss of appetite

Early RA often affects smaller joints, like those in the fingers and toes. As the condition progresses, it may spread to larger joints, including the wrists, knees and shoulders. Symptoms usually affect both sides of the body equally.

About 40% of people with RA may also experience symptoms beyond the joints, affecting areas such as the skin, eyes, lungs, heart, kidneys, salivary glands, nerve tissue and blood vessels.

The symptoms of RA can vary in how severe they are and may come and go. There are times when symptoms get worse, known as flares, followed by periods of improvement, called remission, when discomfort and swelling may lessen or go away. If left untreated, RA can cause joints to change shape or shift over time.

When to see a doctor

What causes rheumatoid arthritis?

Rheumatoid arthritis occurs when the immune system attacks healthy tissues within the joint. Doctors do not know what causes it. Some people are thought to be genetically predisposed to the condition. But environmental triggers, such as chemicals or infections, may cause the immune system to react improperly.

With RA, the immune system releases cells that attack the synovium, a tissue within the joint that produces fluid to ease movement. The cells cause the synovium to become inflamed, which causes pain and other symptoms in your joints. Over time, the synovium becomes thicker and begins damaging surrounding bone and cartilage, which causes the joint to stretch. This stretching causes weakness and instability in the muscles, tendons and ligaments around the joint, which, in turn, may lead to joint deformity, permanent stiffness and other long-term joint damage.

RA risk factors

Factors that may increase your risk of rheumatoid arthritis include:

Age

RA can occur at any age, but it commonly develops in mid-life, usually after age 30.

Possible complications

Seeking help for symptoms of RA allows your doctor to diagnose and treat it early. Although the condition cannot be cured, treatments can prevent it from getting worse and causing other conditions, such as:

  • Anemia: RA can lower your red blood cell count, a condition known as anemia.
  • Cardiovascular disease: People with rheumatoid arthritis have a higher risk of cardiovascular disease, which includes conditions like heart attack and stroke, though the exact reason for this increased risk is unclear.
  • Carpal tunnel syndrome: Carpal tunnel syndrome, common in people with rheumatoid arthritis, occurs due to compression of the median nerve and causes symptoms like aching, numbness and tingling in the hand.
  • Widespread inflammation: Rheumatoid arthritis can cause widespread inflammation in the body, affecting the lungs (leading to chest pain and shortness of breath), heart (causing pericarditis and chest pain), eyes (causing pain or dryness), and blood vessels (leading to vasculitis, which can restrict blood flow and be life-threatening).
  • Osteoporosis: Rheumatoid arthritis and some of its treatments can affect bone mass, making you more prone to osteoporosis.
  • Permanent joint damage: If rheumatoid arthritis isn't treated early or controlled, joint inflammation can cause permanent damage, including harm to bones, cartilage, tendons (which may rupture) and joint deformities.
  • Rheumatoid nodules: Rheumatoid arthritis may cause small bumps to form under the skin.
doctor discussing rheumatoid arthritis complications with a patient

How is rheumatoid arthritis diagnosed?

Diagnosing rheumatoid arthritis usually includes a physical exam, imaging tests and blood tests. If RA is in very early stages when you see your doctor, it may be difficult to diagnose because symptoms may be mild and not clearly linked to the condition.

Rheumatoid arthritis treatment

Although there is no cure for RA, treatment can help you manage symptoms, slow the progression of your condition and lower your chances of developing complications. Doctors from different specialties treat various aspects of rheumatoid arthritis, so you may work with a primary care provider, rheumatologist or orthopedic surgeon during your treatment.

Treatment typically starts with medications, but your provider may also recommend making certain lifestyle changes and receiving physical or occupational therapy. You may need surgery if you have severe joint damage or pain that interferes with your ability to go about your daily life.

Medication

Medications help many people with RA improve their quality of life. Some medications relieve inflammation and other symptoms, while others stop or slow the condition from progressing. You will likely take more than one type of medication.

  • Corticosteroid injections: Your doctor may recommend these injections to address joint pain in the short term.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs can help control pain and swelling. Many types, including ibuprofen and naproxen, are available over the counter, but your doctor can prescribe stronger NSAIDs if over-the-counter medications don’t bring adequate relief.
  • Disease-modifying antirheumatic drugs (DMARDs): These medications help prevent your immune system from attacking your joints, preventing RA from worsening. There are many types of DMARDs, some given in pill form and some delivered by injection or intravenous (IV) infusion.
  • Janus kinase (JAK) inhibitors: JAK inhibitors are a type of DMARD your doctor may recommend if your first treatment isn’t effective. These medications help prevent immune cells from causing the inflammation that causes pain and joint deterioration.

Find a location near you

We offer several locations for your care, including specialty arthritis centers in North and Central Texas.

Baylor Scott & White 65+ Clinic

4716 Alliance Blvd Ste 500, Plano, TX, 75093

Accepting walk-ins

Baylor Scott & White Family Medicine Residency - Waxahachie

2460 N Interstate 35E Ste 215, Waxahachie, TX, 75165

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Avery Ranch

15004 Avery Ranch Blvd Bldg C, Ste 101, Austin, TX, 78717

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Burleson

12500 South Fwy Ste 201, Burleson, TX, 76028

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Cedar Park East

701 East Whitestone Blvd Ste 100, Cedar Park, TX, 78613

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Cedar Park West

500 W Whitestone Blvd Ste 101, Cedar Park, TX, 78613

Not accepting walk-ins

Not accepting walk-ins

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Far West

6818 Austin Center Blvd Ste 111, Austin, TX, 78731

Not accepting walk-ins

Not accepting walk-ins

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Ft Worth Bryant Irvin

4901 Bryant Irving Rd N Ste 200, Fort Worth, TX, 76107

Not accepting walk-ins

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Georgetown

4112 Williams Dr Ste 103, Georgetown, TX, 78628

Not accepting walk-ins

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Grapevine

1643 Lancaster Dr Ste 100, Grapevine, TX, 76051

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Hutto

567 FM 685 (Chris Kelley Blvd) , Hutto, TX, 78634

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Irving MacArthur

2001 N MacArthur Blvd Bldg I, Ste 550, Irving, TX, 75061

Not accepting walk-ins

Not accepting walk-ins

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Liberty Hill

14125 W State Hwy 29 Ste B204, Liberty Hill, TX, 78642

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Little Elm

2700 E Eldorado Pkwy Ste 409, Little Elm, TX, 75068

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Manor

12400 Gregg Manor Rd Ste 101, Manor, TX, 78653

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - McKinney Eldorado

2960 Eldorado Pkwy Ste 75, McKinney, TX, 75070

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - McKinney Lake Forest

5236 W University Dr Ste 3500, McKinney, TX, 75071

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - McKinney Red Bud

1705 W University Dr Ste 119, McKinney, TX, 75069

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Mesquite Belt Line

1313 N Belt Line Rd Ste 102, Mesquite, TX, 75149

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Mesquite Republic

1650 Republic Pkwy Ste 103, Mesquite, TX, 75150

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Mid-Cities

6501 Precinct Line Rd Ste 200, North Richland Hills, TX, 76182

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Midlothian

1441 S Midlothian Pkwy Ste 170, Midlothian, TX, 76065

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Murphy

511 W FM 544 Ste 208, Murphy, TX, 75094

Not accepting walk-ins

Not accepting walk-ins

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - North Garland

7217 Telecom Pkwy Ste 200, Garland, TX, 75044

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Pflugerville

16051 Dessau Rd Ste A, Pflugerville, TX, 78660

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Plano Alliance

4825 Alliance Blvd Ste 200, Plano, TX, 75093

Not accepting walk-ins

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Red River

3200 Red River St Ste 101, Austin, TX, 78705

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Richardson Collins

1740 N Collins Blvd Ste 100, Richardson, TX, 75080

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Round Rock

116 Sundance Pkwy Ste 400, Round Rock, TX, 78681

Not accepting walk-ins

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - South Grand Prairie

2950 W Camp Wisdom Rd Ste 200, Grand Prairie, TX, 75052

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - South Lamar

3901 S Lamar Blvd Ste 140, Austin, TX, 78704

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Terrell

512 American Wy Ste E4, E5, E6, Terrell, TX, 75160

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - The Colony

4897 State Highway 121 , The Colony, TX, 75056

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Waxahachie

2460 N Interstate 35E Ste 260, Waxahachie, TX, 75165

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Weatherford

2035 Fort Worth Hwy Ste 300, Weatherford, TX, 76086

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - West 38th St.

711 W 38th St Suites B3 & B4, Austin, TX, 78705

Not accepting walk-ins

Baylor Scott & White Institute for Rehabilitation - Wylie

600 Cooper Dr Ste 130, Wylie, TX, 75098

Not accepting walk-ins

Frequently asked questions

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