What is rheumatoid arthritis?
Rheumatoid arthritis (RA) is a chronic autoimmune condition that causes discomfort, swelling and stiffness in the lining of your joints. It most often affects joints in your fingers, hands, wrists, knees, ankles, feet and toes. Unlike other types of arthritis, RA typically affects joints on both sides of the body.
An autoimmune condition happens when the immune system, which normally protects the body, becomes confused and starts attacking healthy tissues. In rheumatoid arthritis, this happens when the immune system causes inflammation in the joints.
You can manage RA effectively if it is diagnosed early. However, if left untreated, the condition causes serious side effects, such as joint deformities and disability.
Rheumatoid arthritis symptoms
Signs and symptoms of rheumatoid arthritis may include:
- Pain, aching or stiffness in more than one joint
- Tender, warm, swollen joints
- Stiffness, especially in the mornings or after periods of inactivity
- Fatigue
- Fever
- Loss of appetite
Early RA often affects smaller joints, like those in the fingers and toes. As the condition progresses, it may spread to larger joints, including the wrists, knees and shoulders. Symptoms usually affect both sides of the body equally.
About 40% of people with RA may also experience symptoms beyond the joints, affecting areas such as the skin, eyes, lungs, heart, kidneys, salivary glands, nerve tissue and blood vessels.
The symptoms of RA can vary in how severe they are and may come and go. There are times when symptoms get worse, known as flares, followed by periods of improvement, called remission, when discomfort and swelling may lessen or go away. If left untreated, RA can cause joints to change shape or shift over time.
When to see a doctor
See your doctor if you experience joint pain or other symptoms that last three or more days. You should also see a doctor if you develop joint pain multiple times a month.
RA can cause permanent joint damage. An early diagnosis allows you to receive treatment for the condition before long-term damage occurs, and can offer relief from symptoms.
What causes rheumatoid arthritis?
Rheumatoid arthritis occurs when the immune system attacks healthy tissues within the joint. Doctors do not know what causes it. Some people are thought to be genetically predisposed to the condition. But environmental triggers, such as chemicals or infections, may cause the immune system to react improperly.
With RA, the immune system releases cells that attack the synovium, a tissue within the joint that produces fluid to ease movement. The cells cause the synovium to become inflamed, which causes pain and other symptoms in your joints. Over time, the synovium becomes thicker and begins damaging surrounding bone and cartilage, which causes the joint to stretch. This stretching causes weakness and instability in the muscles, tendons and ligaments around the joint, which, in turn, may lead to joint deformity, permanent stiffness and other long-term joint damage.
RA risk factors
Factors that may increase your risk of rheumatoid arthritis include:
Age
RA can occur at any age, but it commonly develops in mid-life, usually after age 30.
Possible complications
Seeking help for symptoms of RA allows your doctor to diagnose and treat it early. Although the condition cannot be cured, treatments can prevent it from getting worse and causing other conditions, such as:
- Anemia: RA can lower your red blood cell count, a condition known as anemia.
- Cardiovascular disease: People with rheumatoid arthritis have a higher risk of cardiovascular disease, which includes conditions like heart attack and stroke, though the exact reason for this increased risk is unclear.
- Carpal tunnel syndrome: Carpal tunnel syndrome, common in people with rheumatoid arthritis, occurs due to compression of the median nerve and causes symptoms like aching, numbness and tingling in the hand.
- Widespread inflammation: Rheumatoid arthritis can cause widespread inflammation in the body, affecting the lungs (leading to chest pain and shortness of breath), heart (causing pericarditis and chest pain), eyes (causing pain or dryness), and blood vessels (leading to vasculitis, which can restrict blood flow and be life-threatening).
- Osteoporosis: Rheumatoid arthritis and some of its treatments can affect bone mass, making you more prone to osteoporosis.
- Permanent joint damage: If rheumatoid arthritis isn't treated early or controlled, joint inflammation can cause permanent damage, including harm to bones, cartilage, tendons (which may rupture) and joint deformities.
- Rheumatoid nodules: Rheumatoid arthritis may cause small bumps to form under the skin.
How is rheumatoid arthritis diagnosed?
Diagnosing rheumatoid arthritis usually includes a physical exam, imaging tests and blood tests. If RA is in very early stages when you see your doctor, it may be difficult to diagnose because symptoms may be mild and not clearly linked to the condition.
Rheumatoid arthritis treatment
Although there is no cure for RA, treatment can help you manage symptoms, slow the progression of your condition and lower your chances of developing complications. Doctors from different specialties treat various aspects of rheumatoid arthritis, so you may work with a primary care provider, rheumatologist or orthopedic surgeon during your treatment.
Treatment typically starts with medications, but your provider may also recommend making certain lifestyle changes and receiving physical or occupational therapy. You may need surgery if you have severe joint damage or pain that interferes with your ability to go about your daily life.
Medication
Medications help many people with RA improve their quality of life. Some medications relieve inflammation and other symptoms, while others stop or slow the condition from progressing. You will likely take more than one type of medication.
- Corticosteroid injections: Your doctor may recommend these injections to address joint pain in the short term.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs can help control pain and swelling. Many types, including ibuprofen and naproxen, are available over the counter, but your doctor can prescribe stronger NSAIDs if over-the-counter medications don’t bring adequate relief.
- Disease-modifying antirheumatic drugs (DMARDs): These medications help prevent your immune system from attacking your joints, preventing RA from worsening. There are many types of DMARDs, some given in pill form and some delivered by injection or intravenous (IV) infusion.
- Janus kinase (JAK) inhibitors: JAK inhibitors are a type of DMARD your doctor may recommend if your first treatment isn’t effective. These medications help prevent immune cells from causing the inflammation that causes pain and joint deterioration.
Find a location near you
We offer several locations for your care, including specialty arthritis centers in North and Central Texas.

4716 Alliance Blvd Ste 500, Plano, TX, 75093
4716 Alliance Blvd Ste 500, Plano, TX, 75093
Accepting walk-ins
Patients in line:

2460 N Interstate 35E Ste 215, Waxahachie, TX, 75165
2460 N Interstate 35E Ste 215, Waxahachie, TX, 75165
Not accepting walk-ins
Patients in line:

15004 Avery Ranch Blvd Bldg C, Ste 101, Austin, TX, 78717
15004 Avery Ranch Blvd Bldg C, Ste 101, Austin, TX, 78717
Not accepting walk-ins
Patients in line:

12500 South Fwy Ste 201, Burleson, TX, 76028
12500 South Fwy Ste 201, Burleson, TX, 76028
Not accepting walk-ins
Patients in line:

1850 Legends Trl , Carrollton, TX, 75006
1850 Legends Trl , Carrollton, TX, 75006
Not accepting walk-ins
Patients in line:

701 East Whitestone Blvd Ste 100, Cedar Park, TX, 78613
701 East Whitestone Blvd Ste 100, Cedar Park, TX, 78613
Not accepting walk-ins
Patients in line:

500 W Whitestone Blvd Ste 101, Cedar Park, TX, 78613
500 W Whitestone Blvd Ste 101, Cedar Park, TX, 78613
Not accepting walk-ins
Patients in line:

1015 N Carroll Ave Ste 100, Dallas, TX, 75204
1015 N Carroll Ave Ste 100, Dallas, TX, 75204
Not accepting walk-ins
Patients in line:

411 N Washington Ave Ste 3900, Dallas, TX, 75246
411 N Washington Ave Ste 3900, Dallas, TX, 75246
Not accepting walk-ins
Patients in line:

6818 Austin Center Blvd Ste 111, Austin, TX, 78731
6818 Austin Center Blvd Ste 111, Austin, TX, 78731
Not accepting walk-ins
Patients in line:

3621 Camp Bowie Blvd , Fort Worth, TX, 76107
3621 Camp Bowie Blvd , Fort Worth, TX, 76107
Not accepting walk-ins
Patients in line:

5858 Main St Ste 160, Frisco, TX, 75033
5858 Main St Ste 160, Frisco, TX, 75033
Not accepting walk-ins
Patients in line:

4901 Bryant Irving Rd N Ste 200, Fort Worth, TX, 76107
4901 Bryant Irving Rd N Ste 200, Fort Worth, TX, 76107
Not accepting walk-ins
Patients in line:

333 N Shiloh Rd Ste 108, Garland, TX, 75042
333 N Shiloh Rd Ste 108, Garland, TX, 75042
Not accepting walk-ins
Patients in line:

4112 Williams Dr Ste 103, Georgetown, TX, 78628
4112 Williams Dr Ste 103, Georgetown, TX, 78628
Not accepting walk-ins
Patients in line:

5353 Williams Dr Ste 100, Georgetown, TX, 78633
5353 Williams Dr Ste 100, Georgetown, TX, 78633
Not accepting walk-ins
Patients in line:

1643 Lancaster Dr Ste 100, Grapevine, TX, 76051
1643 Lancaster Dr Ste 100, Grapevine, TX, 76051
Not accepting walk-ins
Patients in line:

567 FM 685 (Chris Kelley Blvd) , Hutto, TX, 78634
567 FM 685 (Chris Kelley Blvd) , Hutto, TX, 78634
Not accepting walk-ins
Patients in line:

2001 N MacArthur Blvd Bldg I, Ste 550, Irving, TX, 75061
2001 N MacArthur Blvd Bldg I, Ste 550, Irving, TX, 75061
Not accepting walk-ins
Patients in line:

5695 Kyle Pkwy Ste 140, Kyle, TX, 78640
5695 Kyle Pkwy Ste 140, Kyle, TX, 78640
Not accepting walk-ins
Patients in line:

1007 S Highway 183 , Leander, TX, 78641
1007 S Highway 183 , Leander, TX, 78641
Not accepting walk-ins
Patients in line:

14125 W State Hwy 29 Ste B204, Liberty Hill, TX, 78642
14125 W State Hwy 29 Ste B204, Liberty Hill, TX, 78642
Not accepting walk-ins
Patients in line:

2700 E Eldorado Pkwy Ste 409, Little Elm, TX, 75068
2700 E Eldorado Pkwy Ste 409, Little Elm, TX, 75068
Not accepting walk-ins
Patients in line:

12400 Gregg Manor Rd Ste 101, Manor, TX, 78653
12400 Gregg Manor Rd Ste 101, Manor, TX, 78653
Not accepting walk-ins
Patients in line:

2960 Eldorado Pkwy Ste 75, McKinney, TX, 75070
2960 Eldorado Pkwy Ste 75, McKinney, TX, 75070
Not accepting walk-ins
Patients in line:

5236 W University Dr Ste 3500, McKinney, TX, 75071
5236 W University Dr Ste 3500, McKinney, TX, 75071
Not accepting walk-ins
Patients in line:

1705 W University Dr Ste 119, McKinney, TX, 75069
1705 W University Dr Ste 119, McKinney, TX, 75069
Not accepting walk-ins
Patients in line:

1313 N Belt Line Rd Ste 102, Mesquite, TX, 75149
1313 N Belt Line Rd Ste 102, Mesquite, TX, 75149
Not accepting walk-ins
Patients in line:

1650 Republic Pkwy Ste 103, Mesquite, TX, 75150
1650 Republic Pkwy Ste 103, Mesquite, TX, 75150
Not accepting walk-ins
Patients in line:

6501 Precinct Line Rd Ste 200, North Richland Hills, TX, 76182
6501 Precinct Line Rd Ste 200, North Richland Hills, TX, 76182
Not accepting walk-ins
Patients in line:

1441 S Midlothian Pkwy Ste 170, Midlothian, TX, 76065
1441 S Midlothian Pkwy Ste 170, Midlothian, TX, 76065
Not accepting walk-ins
Patients in line:

511 W FM 544 Ste 208, Murphy, TX, 75094
511 W FM 544 Ste 208, Murphy, TX, 75094
Not accepting walk-ins
Patients in line:

4120 SH 360 Suite 105, Fort Worth, TX, 76155
4120 SH 360 Suite 105, Fort Worth, TX, 76155
Not accepting walk-ins
Patients in line:

510 N Coit Rd Ste 2035, Richardson, TX, 75080
510 N Coit Rd Ste 2035, Richardson, TX, 75080
Not accepting walk-ins
Patients in line:

7217 Telecom Pkwy Ste 200, Garland, TX, 75044
7217 Telecom Pkwy Ste 200, Garland, TX, 75044
Not accepting walk-ins
Patients in line:

16051 Dessau Rd Ste A, Pflugerville, TX, 78660
16051 Dessau Rd Ste A, Pflugerville, TX, 78660
Not accepting walk-ins
Patients in line:

4825 Alliance Blvd Ste 200, Plano, TX, 75093
4825 Alliance Blvd Ste 200, Plano, TX, 75093
Not accepting walk-ins
Patients in line:

4701 W Parker Rd Ste 625, Plano, TX, 75093
4701 W Parker Rd Ste 625, Plano, TX, 75093
Not accepting walk-ins
Patients in line:

3200 Red River St Ste 101, Austin, TX, 78705
3200 Red River St Ste 101, Austin, TX, 78705
Not accepting walk-ins
Patients in line:

1740 N Collins Blvd Ste 100, Richardson, TX, 75080
1740 N Collins Blvd Ste 100, Richardson, TX, 75080
Not accepting walk-ins
Patients in line:

116 Sundance Pkwy Ste 400, Round Rock, TX, 78681
116 Sundance Pkwy Ste 400, Round Rock, TX, 78681
Not accepting walk-ins
Patients in line:

300A University Blvd , Round Rock, TX, 78665
300A University Blvd , Round Rock, TX, 78665
Not accepting walk-ins
Patients in line:

2950 W Camp Wisdom Rd Ste 200, Grand Prairie, TX, 75052
2950 W Camp Wisdom Rd Ste 200, Grand Prairie, TX, 75052
Not accepting walk-ins
Patients in line:

3901 S Lamar Blvd Ste 140, Austin, TX, 78704
3901 S Lamar Blvd Ste 140, Austin, TX, 78704
Not accepting walk-ins
Patients in line:

512 American Wy Ste E4, E5, E6, Terrell, TX, 75160
512 American Wy Ste E4, E5, E6, Terrell, TX, 75160
Not accepting walk-ins
Patients in line:

4897 State Highway 121 , The Colony, TX, 75056
4897 State Highway 121 , The Colony, TX, 75056
Not accepting walk-ins
Patients in line:

2460 N Interstate 35E Ste 260, Waxahachie, TX, 75165
2460 N Interstate 35E Ste 260, Waxahachie, TX, 75165
Not accepting walk-ins
Patients in line:

2035 Fort Worth Hwy Ste 300, Weatherford, TX, 76086
2035 Fort Worth Hwy Ste 300, Weatherford, TX, 76086
Not accepting walk-ins
Patients in line:

711 W 38th St Suites B3 & B4, Austin, TX, 78705
711 W 38th St Suites B3 & B4, Austin, TX, 78705
Not accepting walk-ins
Patients in line:

600 Cooper Dr Ste 130, Wylie, TX, 75098
600 Cooper Dr Ste 130, Wylie, TX, 75098
Not accepting walk-ins
Patients in line:
Frequently asked questions
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