What is endocarditis?
Endocarditis is inflammation of the endocardium, the layer of tissue that lines your heart valves and chambers. Most often caused by an infection, endocarditis occurs when germs enter your bloodstream, travel to the heart and attach to the endocardium—usually to the surfaces of one of the four heart valves. Without swift treatment, endocarditis can cause serious health problems and may be life-threatening.
Types of endocarditis
Providers often refer to endocarditis as infective, as most cases are caused by a bacterial infection, but it can also be caused by a viral or fungal infection. Bacteria or fungi join with proteins and blood cells to form clumps called vegetations on the endocardium. If these buildups break loose, they can cause a spread of the infection to other organs or restrict blood flow to organs such as the heart or brain.
Less commonly, endocarditis can be noninfective, which means only proteins and blood cells form vegetations. Doctors aren’t sure why noninfective endocarditis occurs.
Endocarditis is also categorized by how quickly or when it develops. Types include:
- Acute endocarditis: This type develops suddenly and, within days, may become life-threatening, which makes prompt treatment essential.
- Subacute endocarditis: This type forms more slowly than acute endocarditis, taking weeks or months to develop.
- Prosthetic valvular endocarditis: This type develops after heart valve replacement surgery if the germs become attached to the prosthetic valve.
Endocarditis symptoms
Endocarditis symptoms vary from person to person depending on the type of infection. With acute endocarditis, symptoms may occur without warning. With subacute endocarditis, symptoms may develop gradually. Severe symptoms may make you feel very ill. Some people, though, experience only mild symptoms.
Symptoms of endocarditis include:
- Back, muscle or joint pain
- Blood in your urine
- Chest pain
- Chills
- Cough
- Fatigue
- Fever
- Heart murmur
- Night sweats
- Red or purple bumps or other skin changes
- Shortness of breath
- Stomach pain
- Weight loss
When to see a doctor
See your primary care doctor if you have endocarditis symptoms or signs of an infection, such as a fever and body aches. Endocarditis is rare, and having an infection does not mean you will necessarily develop the infection in your heart. Still, seeking treatment for an infection as soon as possible can help you avoid serious complications. Similarly, diagnosing and treating endocarditis quickly protects your heart from long-term damage.
Endocarditis causes
In most cases, endocarditis occurs due to infection by bacteria. These bacteria may live on your body or in your mouth. They may also come from an infection elsewhere in your body, such as the urinary tract. Bacteria can enter your bloodstream through cuts or scratches or during dental or surgical procedures.
Less commonly, infections with yeast or other fungi can also cause endocarditis. Yeast, like some bacteria, can also live on your body and enter the bloodstream through wounds or surgery.
Endocarditis risk factors
Many factors can increase your risk for endocarditis. Some of these factors, such as having certain heart conditions or a weakened immune system, are outside of your control. However, other factors, such as poor oral or skin health, are within your control.
Knowing your risk factors can help you and your doctor understand your chances of developing endocarditis, and you can take steps to prevent infection and protect your heart.
Risk factors for endocarditis include:
- Age: Adults older than 65 are more likely to get endocarditis. Age-related changes to the heart valves, such as calcium deposits, give germs more landing spots.
- A history of endocarditis: If you’ve had endocarditis before, your heart tissue may have sustained damage that makes additional inflammation more likely.
- Artificial heart valves: Bacteria may be better able to attach to the foreign material of a prosthetic heart valve than native valve tissue.
- Congenital heart disease: Heart abnormalities that exist at birth, such as narrow valves, provide easier places for germs to collect.
- Heart valve disease: If you have a damaged heart valve, germs may be able to attach to it more easily.
- Implanted heart devices: Bacteria may attach to a pacemaker, cardioverter defibrillator or another implanted device, and trigger inflammation.
- Long-term IV use: Consistently receiving medications or using illicit drugs through an IV may allow germs to enter the bloodstream.
- Poor oral health: Not taking care of your teeth and gums can allow bacteria to build up and, potentially, enter the bloodstream.
- Weakened immune system: If your immune system isn’t as strong as it should be, it may struggle to destroy invading bacteria or fungi.
Complications
Without timely treatment, endocarditis can lead to serious health problems or death. Certain serious health problems can occur if the vegetations that form on the endocardium break free and block blood flow to important organs. In other cases, complications may arise due to damage to the heart or your body’s reaction to the infection.
Possible complications of endocarditis include:
- Abscesses: Vegetations on the endocardium may cause abscesses (pockets of pus) to form near the affected tissue.
- Arrhythmia: Damage to the heart may interfere with the organ’s pumping ability and cause it to beat irregularly.
- Heart attack: A vegetation that breaks loose from the endocardium may block an artery in the heart, causing a heart attack.
- Heart failure: If endocarditis damages the heart valves, the heart may have to work harder to pump blood, leading to heart failure.
- Heart valve damage: Vegetations that form on the endocardium can cause holes in the valves, which may worsen their function.
- Sepsis: This condition occurs when your body overreacts to an infection, potentially leading to dangerously low blood pressure and organ failure.
- Stroke: A stroke may occur if a vegetation separates from the endocardium and blocks an artery that feeds blood to the brain.
Diagnosing endocarditis
Your doctor will ask about your health history, including any heart conditions or procedures that could increase your risk for endocarditis. They will also want to learn about your symptoms. The doctor will check you for signs of endocarditis, such as a heart murmur. Finally, they will order blood and imaging tests to look for infection and determine how well your heart is working.
Endocarditis treatment
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If your doctor diagnoses endocarditis, they will begin treatment quickly to prevent serious complications. You will receive medication to treat the microorganisms responsible for the infection.
Medication
Doctors use two main types of medication to treat endocarditis. Which type you receive depends on what caused the infection.
- Antibiotics: If you have bacterial endocarditis, you’ll receive antibiotics. At first, you may get a medication that targets a wide range of bacteria. Later, though, doctors may change the medication to treat the specific bacteria responsible for your infection.
If you need antibiotics, you will likely stay in the hospital for several days so you can receive medication through an IV. During this time, doctors will monitor your response to the medication to ensure your symptoms improve. You may need antibiotics for several weeks to eliminate the infection. - Antifungals: You’ll need an antifungal medication for endocarditis caused by fungi. You may need to take this medication for the rest of your life to prevent future inflammation of the endocardium.
If endocarditis damages a heart valve or keeps returning, heart valve surgery may be necessary.
Locations for endocarditis care
Our heart teams in North and Central Texas have the expertise necessary to treat endocarditis and its possible complications. We can help arrange your care at the location best suited to your needs.

5701 Bryant Irvin Rd Ste 302, Fort Worth, TX, 76132
5701 Bryant Irvin Rd Ste 302, Fort Worth, TX, 76132
Not accepting walk-ins
Patients in line:

1219 E South 11th St Ste B2, Abilene, TX, 79602
1219 E South 11th St Ste B2, Abilene, TX, 79602
Not accepting walk-ins
Patients in line:

1901 Medi Park Dr Ste 2051, Amarillo, TX, 79106
1901 Medi Park Dr Ste 2051, Amarillo, TX, 79106
Not accepting walk-ins
Patients in line:

3410 Worth St Ste 250, Dallas, TX, 75246
3410 Worth St Ste 250, Dallas, TX, 75246
Not accepting walk-ins
Patients in line:

906 Judson Rd , Longview, TX, 75601
906 Judson Rd , Longview, TX, 75601
Not accepting walk-ins
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3711 22nd St Ste B, Lubbock, TX, 79410
3711 22nd St Ste B, Lubbock, TX, 79410
Not accepting walk-ins
Patients in line:

420 E 6th St Ste 102, Odessa, TX, 79761
420 E 6th St Ste 102, Odessa, TX, 79761
Not accepting walk-ins
Patients in line:

1321 S Beckham Ave , Tyler, TX, 75701
1321 S Beckham Ave , Tyler, TX, 75701
Not accepting walk-ins
Patients in line:

1250 8th Ave Ste 200, Fort Worth, TX, 76104
1250 8th Ave Ste 200, Fort Worth, TX, 76104
Not accepting walk-ins
Patients in line:

1400 8th Ave , Fort Worth, TX, 76104
1400 8th Ave , Fort Worth, TX, 76104
Accepting walk-ins
Patients in line:

3333 Colorado Blvd , Denton, TX, 76210
3333 Colorado Blvd , Denton, TX, 76210
Not accepting walk-ins
Patients in line:

16050 Everwell Ln Ste 210, Frisco, TX, 75033
16050 Everwell Ln Ste 210, Frisco, TX, 75033
Not accepting walk-ins
Patients in line:

7217 Telecom Pkwy Ste 205, Garland, TX, 75044
7217 Telecom Pkwy Ste 205, Garland, TX, 75044
Not accepting walk-ins
Patients in line:

2020 W State Hwy 114 Ste 320, Grapevine, TX, 76051
2020 W State Hwy 114 Ste 320, Grapevine, TX, 76051
Not accepting walk-ins
Patients in line:

1401 Shoal Creek Ste 240, Highland Village, TX, 75077
1401 Shoal Creek Ste 240, Highland Village, TX, 75077
Not accepting walk-ins
Patients in line:

5236 W University Dr POB I, Ste 4900, McKinney, TX, 75071
5236 W University Dr POB I, Ste 4900, McKinney, TX, 75071
Not accepting walk-ins
Patients in line:

1820 Preston Park Blvd Ste 1450, Plano, TX, 75093
1820 Preston Park Blvd Ste 1450, Plano, TX, 75093
Not accepting walk-ins
Patients in line:

111 S Preston Rd Ste 10, Prosper, TX, 75078
111 S Preston Rd Ste 10, Prosper, TX, 75078
Not accepting walk-ins
Patients in line:

1250 8th Ave Ste 200, Fort Worth, TX, 76104
1250 8th Ave Ste 200, Fort Worth, TX, 76104
Not accepting walk-ins
Patients in line:

3711 22nd St Ste B, Lubbock, TX, 79410
3711 22nd St Ste B, Lubbock, TX, 79410
Not accepting walk-ins
Patients in line:

420 E 6th St Ste 102, Odessa, TX, 79761
420 E 6th St Ste 102, Odessa, TX, 79761
Not accepting walk-ins
Patients in line:

2035 Fort Worth Hwy Ste 100, Weatherford, TX, 76086
2035 Fort Worth Hwy Ste 100, Weatherford, TX, 76086
Not accepting walk-ins
Patients in line:

621 N Hall St Ste 120, Dallas, TX, 75226
621 N Hall St Ste 120, Dallas, TX, 75226
Not accepting walk-ins
Patients in line:

3333 Colorado Blvd , Denton, TX, 76210
3333 Colorado Blvd , Denton, TX, 76210
Not accepting walk-ins
Patients in line:

5236 W University Dr Ste 4900, McKinney, TX, 75071
5236 W University Dr Ste 4900, McKinney, TX, 75071
Not accepting walk-ins
Patients in line:

4708 Alliance Blvd Pavilion I, Ste 540, Plano, TX, 75093
4708 Alliance Blvd Pavilion I, Ste 540, Plano, TX, 75093
Not accepting walk-ins
Patients in line:

621 N Hall St Ste 500, Dallas, TX, 75226
621 N Hall St Ste 500, Dallas, TX, 75226
Not accepting walk-ins
Patients in line:

4400 Interstate 30 W Ste 300, Greenville, TX, 75402
4400 Interstate 30 W Ste 300, Greenville, TX, 75402
Not accepting walk-ins
Patients in line:

1575 Interstate 30 , Mesquite, TX, 75150
1575 Interstate 30 , Mesquite, TX, 75150
Not accepting walk-ins
Patients in line:

4431 E US Hwy 287 , Midlothian, TX, 76065
4431 E US Hwy 287 , Midlothian, TX, 76065
Not accepting walk-ins
Patients in line:

9101 N Central Expy Ste 300C, Dallas, TX, 75231
9101 N Central Expy Ste 300C, Dallas, TX, 75231
Not accepting walk-ins
Patients in line:

301 E Ovilla Rd Ste 100, Red Oak, TX, 75154
301 E Ovilla Rd Ste 100, Red Oak, TX, 75154
Not accepting walk-ins
Patients in line:

2360 N Interstate 35E Ste 110, Waxahachie, TX, 75165
2360 N Interstate 35E Ste 110, Waxahachie, TX, 75165
Not accepting walk-ins
Patients in line:

1110 Cottonwood Ln Ste 215, Irving, TX, 75038
1110 Cottonwood Ln Ste 215, Irving, TX, 75038
Not accepting walk-ins
Patients in line:

1307 8th Ave Ste 406, Fort Worth, TX, 76104
1307 8th Ave Ste 406, Fort Worth, TX, 76104
Not accepting walk-ins
Patients in line:

3333 Colorado Blvd , Denton, TX, 76210
3333 Colorado Blvd , Denton, TX, 76210
Not accepting walk-ins
Patients in line:

16050 Everwell Ln Ste 210, Frisco, TX, 75033
16050 Everwell Ln Ste 210, Frisco, TX, 75033
Not accepting walk-ins
Patients in line:

2020 W State Hwy 114 Ste 200, Grapevine, TX, 76051
2020 W State Hwy 114 Ste 200, Grapevine, TX, 76051
Not accepting walk-ins
Patients in line:

1401 Shoal Creek Ste 240, Highland Village, TX, 75077
1401 Shoal Creek Ste 240, Highland Village, TX, 75077
Not accepting walk-ins
Patients in line:

620 S Main St Ste 240, Keller, TX, 76248
620 S Main St Ste 240, Keller, TX, 76248
Not accepting walk-ins
Patients in line:

6000 W Spring Creek Pkwy Ste 220, Plano, TX, 75024
6000 W Spring Creek Pkwy Ste 220, Plano, TX, 75024
Not accepting walk-ins
Patients in line:

4708 Alliance Blvd Pavilion I, Ste 450 , Plano, TX, 75093
4708 Alliance Blvd Pavilion I, Ste 450 , Plano, TX, 75093
Not accepting walk-ins
Patients in line:

3800 Gaylord Pkwy Ste 910, Frisco, TX, 75034
3800 Gaylord Pkwy Ste 910, Frisco, TX, 75034
Not accepting walk-ins
Patients in line:

5308 N Galloway Ave Ste 201, Mesquite, TX, 75150
5308 N Galloway Ave Ste 201, Mesquite, TX, 75150
Not accepting walk-ins
Patients in line:

6705 Heritage Pkwy Ste 202, Rockwall, TX, 75087
6705 Heritage Pkwy Ste 202, Rockwall, TX, 75087
Not accepting walk-ins
Patients in line:

3410 Worth St Ste 760, Dallas, TX, 75246
3410 Worth St Ste 760, Dallas, TX, 75246
Not accepting walk-ins
Patients in line:

3711 22nd St Ste B, Lubbock, TX, 79410
3711 22nd St Ste B, Lubbock, TX, 79410
Not accepting walk-ins
Patients in line:

6701 Heritage Pkwy Ste 130, Rockwall, TX, 75087
6701 Heritage Pkwy Ste 130, Rockwall, TX, 75087
Not accepting walk-ins
Patients in line:

1321 S Beckham Ave , Tyler, TX, 75702
1321 S Beckham Ave , Tyler, TX, 75702
Not accepting walk-ins
Patients in line:

2480 N Interstate 35E , Waxahachie, TX, 75165
2480 N Interstate 35E , Waxahachie, TX, 75165
Not accepting walk-ins
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